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Genome stability : from virus to human application / edited by Igor Kovalchuk, Olga Kovalchuk, University of Lethbridge, Lethbridge, AB, Chanda - Amsterdam : Elsevier, - xxii, 690 pages : illustrations ; 29 cm. - Translational epigenetics series . - Translational epigenetics series. .

Includes bibliographical references and index.

Genome Stability: From Virus to Human Application covers the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, with the latter including major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, as well as changes in genome stability in response to aging. Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. This book teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. The book also covers how epigenetic factors contribute to genome stability and how species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner.

9780128033098 0128033096

2016942133

101699120 DNLM


Genomes.
Genomics.
DNA repair.
DNA Repair.
Genomic Instability.
Epigenesis, Genetic.
DNA repair.
Genomes.
Genomics.

QH447 / GEN 2016

572.8/629

2017 A-444 QU 475